Brown crystals; produce 0.43 g, 87.5%; m.p. = 8.4 Hz), 12.14 (bs, 1H, NH; exchangeable with D2O); 13C-NMR (DMSO(3). Yellow crystals; produce 2.99 g, 91.5%; m.p. 261C262 C; IR (KBr): 1651 (C=O), 3250 cm?1 (NH); 1H-NMR (DMSO-= 8.4 Hz), 12.12 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H18ClNO2 (327.80): C, 69.62; H, 5.53; N, 4.27 Found: C, 69.82; H, 5.76; N, 3.99. (4). Yellow crystals; produce 3.00 g, 93.0%; m.p. 240C241 C; IR (KBr): 1651 (C=O), 3232 cm?1 (NH); 1H-NMR (DMSO-= 8.4 Hz), 7.48 (d, 1H, -COCH=; = 15.3 Hz), 7.60 (d, 1H, CH=; = 15.3 Hz), Bis-PEG1-C-PEG1-CH2COOH 8.01 (d, 2H, ArH; = 8.4 Hz), 12.03 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H21NO3 (323.39): C, 74.28; H, 6.55; N, 4.33 Found: C, 74.40; H, 6.71; N, 4.11. 3.3. General Process of the Planning of Substances = 17.4, 12.0 Hz), 6.92 (s, 1H, CH-pyrrole), 6.97 (d, 2H, ArH; = 8.6 Hz), 7.25 (bs, Bis-PEG1-C-PEG1-CH2COOH 2H, NH2; exchangeable with D2O), 8.01 (d, 2H, ArH; = 8.6 Hz), 12.05 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H21BrN4Operating-system (445.38): C, 53.94; H, 4.75; N, 12.58 Found: C, 53.70; H, 4.60; N, 12.76. = 17.4, 12.0 Hz), 7.58 (s, 1H, CH-pyrrole), 7.47 (bs, 2H, NH2; exchangeable with D2O), 7.77 (d, 2H, ArH; = 7.5 Hz), 7.93 (d, 2H, ArH; = 7.5 Hz), 12.00 (bs, 1H, NH; exchangeable with D2O); 13C-NMR (DMSOand (8). Dark brown crystals; produce 0.31 g, 81.3%; m.p. 210C211 C; IR (KBr): 1641 (C=O), 3260, 3436 cm?1 (NH); 1H-NMR (DMSO-= 7.7 Hz), 7.93 (d, 2H, ArH; = 7.7 Hz), 11.25 (bs, 1H, NH; exchangeable with D2O), 12.08 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H20BrN3O (386.29): C, 59.08; H, 5.22; N, 10.88 Found: C, 59.26; H, 5.45; N, 10.65. (9). Buff crystals; produce 0.26 g, 78.8%; m.p. 195C196 C; IR (KBr): 1642 (C=O), 3209, 3423 cm?1 (NH); 1H-NMR (DMSO-= 7.7 Hz), 7.78 (d, 2H, ArH; = 7.7 Hz), 11.19 (bs, 1H, NH; exchangeable with D2O), 12.07 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H20ClN3O (341.83): C, 66.76; H, 5.90; N, 12.29 Found: C, 66.53; H, 5.69; N, 12.50. 3.5. General Process of the Planning of Substances (10). Yellow crystals; produce 0.34 g, 90.1%; m.p. 115C116 C; IR (KBr): 1646 (C=O), 3423 cm?1 (NH); 1H-NMR (DMSO-(11). Buff crystals; produce 0.26 g, 78.3%; m.p. 160C161 C; IR (KBr): 1643 (C=O), 3433 cm?1 (NH); 1H-NMR (DMSO-= 6.7 Hz), 7.70 (d, 2H, ArH; = 6.7 Hz), 11.97 (bs, 1H, NH; exchangeable with D2O). 13C-NMR (DMSO(12). Buff crystals; produce 0.27 g, 81.0%; m.p. 170C171 C; IR (KBr): 1645 (C=O), 3427 cm?1 (NH); 1H-NMR (DMSO-= 6.9 Hz), 7.62 (d, 2H, ArH; = 6.9 Hz), 11.16 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H22N2O3 (338.40): C, 70.99; H, 6.55; N, 8.28 Found: C, 70.79; H, 6.31; N, 8.47. 3.6. General Process of the Planning of Compounds (13). Brown crystals; yield Bis-PEG1-C-PEG1-CH2COOH 0.48 g, 90.2%; mp 180C181 C; IR (KBr): 1219, 1374 (SO2), 1651 (C=O), 3250, 3434 cm?1 (NH, NH2); 1H-NMR (DMSO-(14). Brown crystals; yield 0.43 g, 87.5%; m.p. 150C151 C; IR (KBr): 1219, 1374 (SO2), 1651 (C=O), 3256, 3438 cm?1 (NH, NH2); 1H-NMR (DMSO-= 17.4, 12.0 Hz), 5.53C5.55 (m, 1H, H5-pyrazoline), 6.85 (s, 1H, CH-pyrrole), 7.13 (d, 2H, ArH; = 9.1 Hz), 7.34 (bs, 2H, NH2; exchangeable with D2O), 7.43 (d, 2H, ArH; = 9.1 Hz), 7.53 (d, 2H, ArH; = 8.4 Hz), 7.69 (d, 2H, ArH; = 8.4 Hz), 12.18 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C25H25ClN4O3S (497.01): C, 60.41; H, 5.07; N, 11.27 Found: C, 60.66; H, 5.30; N, 11.03. (15). Buff crystals; yield 0.44 g, 91.1%; m.p. 224C225 C; IR (KBr): 1158, 1307 (SO2), 1650 (C=O), 3263, 3345 cm?1 (NH, NH2); 1H-NMR (DMSO-= 8.4 Hz), 7.60 (d, 2H, ArH; = 8.4 Hz), 7.70C7.73 (m, 2H, ArH), 11.65 (bs, 1H, NH; exchangeable with D2O). 13C-NMR (DMSO(16). Buff crystals; yield 0.49 g, 79.3%; m.p. 200C201 C; IR (KBr): 1162, 1335 (SO2), 1653 (C=O), 3253, 3433 cm?1 (NH, NH2); 1H-NMR (DMSO-= 7.7 Hz), 7.86 (d, 2H, ArH; = 8.4 Hz), 7.92 (d, 2H, ArH; = 8.4 Hz), 8.07 (d, 2H, ArH; = 7.7.Brown crystals; yield 0.45 g, 86.8%; m.p. NH; exchangeable with D2O); 13C-NMR (DMSO(3). Yellow crystals; yield 2.99 g, 91.5%; m.p. 261C262 C; IR (KBr): 1651 (C=O), 3250 cm?1 Bis-PEG1-C-PEG1-CH2COOH (NH); 1H-NMR (DMSO-= 8.4 Hz), 12.12 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H18ClNO2 (327.80): C, 69.62; H, 5.53; N, 4.27 Found: C, 69.82; H, 5.76; N, 3.99. (4). Yellow crystals; yield 3.00 g, 93.0%; m.p. 240C241 C; IR (KBr): 1651 (C=O), 3232 cm?1 (NH); 1H-NMR (DMSO-= 8.4 Hz), 7.48 (d, 1H, -COCH=; = 15.3 Hz), 7.60 (d, 1H, CH=; = 15.3 Hz), 8.01 (d, 2H, ArH; = 8.4 Hz), 12.03 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H21NO3 (323.39): C, 74.28; H, 6.55; N, 4.33 Found: C, 74.40; H, 6.71; N, 4.11. 3.3. General Procedure for the Preparation of Compounds = 17.4, 12.0 Hz), 6.92 (s, 1H, CH-pyrrole), 6.97 (d, 2H, ArH; = 8.6 Hz), 7.25 (bs, 2H, NH2; exchangeable with D2O), 8.01 (d, 2H, ArH; = 8.6 Hz), 12.05 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H21BrN4OS (445.38): C, 53.94; H, 4.75; N, 12.58 Found: C, 53.70; H, 4.60; N, 12.76. = 17.4, 12.0 Hz), 7.58 (s, 1H, CH-pyrrole), 7.47 (bs, 2H, NH2; exchangeable with D2O), 7.77 (d, 2H, ArH; = 7.5 Hz), 7.93 (d, 2H, ArH; = 7.5 Hz), 12.00 (bs, 1H, NH; exchangeable with D2O); 13C-NMR (DMSOand (8). Brown crystals; yield 0.31 g, 81.3%; m.p. 210C211 C; IR (KBr): 1641 (C=O), 3260, 3436 cm?1 (NH); 1H-NMR (DMSO-= 7.7 Hz), 7.93 (d, 2H, ArH; = 7.7 Hz), 11.25 (bs, 1H, NH; exchangeable with D2O), 12.08 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H20BrN3O (386.29): C, 59.08; H, 5.22; N, 10.88 Found: C, 59.26; H, 5.45; N, 10.65. (9). Buff crystals; yield 0.26 g, 78.8%; m.p. 195C196 C; IR (KBr): 1642 (C=O), 3209, 3423 cm?1 (NH); 1H-NMR (DMSO-= 7.7 Hz), 7.78 (d, 2H, ArH; = 7.7 Hz), 11.19 (bs, 1H, NH; exchangeable with D2O), 12.07 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H20ClN3O (341.83): C, 66.76; H, 5.90; N, 12.29 Found: C, 66.53; H, 5.69; N, 12.50. 3.5. General Procedure for the Preparation of Compounds (10). Yellow crystals; yield 0.34 g, 90.1%; m.p. 115C116 C; IR (KBr): 1646 (C=O), 3423 cm?1 (NH); 1H-NMR (DMSO-(11). Buff crystals; yield 0.26 g, 78.3%; m.p. 160C161 C; IR (KBr): 1643 (C=O), 3433 cm?1 (NH); 1H-NMR (DMSO-= 6.7 Hz), 7.70 (d, 2H, ArH; = 6.7 Hz), 11.97 (bs, 1H, NH; exchangeable with D2O). 13C-NMR (DMSO(12). Buff crystals; yield 0.27 g, 81.0%; m.p. 170C171 C; IR (KBr): 1645 (C=O), 3427 cm?1 (NH); 1H-NMR (DMSO-= 6.9 Hz), 7.62 (d, 2H, ArH; = 6.9 Hz), 11.16 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H22N2O3 (338.40): C, 70.99; H, 6.55; N, 8.28 Found: C, 70.79; H, 6.31; N, 8.47. 3.6. General Procedure for the Preparation of Compounds (13). Brown crystals; yield 0.48 g, 90.2%; mp 180C181 C; IR (KBr): 1219, 1374 (SO2), 1651 (C=O), 3250, 3434 cm?1 (NH, NH2); 1H-NMR (DMSO-(14). Brown crystals; yield 0.43 g, 87.5%; m.p. 150C151 C; IR (KBr): 1219, 1374 (SO2), 1651 (C=O), 3256, 3438 cm?1 (NH, NH2); 1H-NMR (DMSO-= 17.4, 12.0 Hz), 5.53C5.55 (m, 1H, H5-pyrazoline), 6.85 (s, 1H, CH-pyrrole), 7.13.Anal. minim. inhibitory concentration (MIC). and exceeding that of ampicillin, ciprofloxacin and imipenam.. The minimal inhibitory concentration (MIC) value showed that compound 16 has good antimicrobial activity against (2). Yellow crystals; yield 3.36 g, 90.5%; m.p. 269C270 C; IR (KBr): 1651 (C=O), 3252 cm?1 (NH); 1H-NMR (DMSO-= 15.3 Hz), 7.60 (d, 1H, CH=; = 15.3 Hz), 7.76 (d, 2H, ArH; 8.4 Hz), 7.93 (d, 2H, ArH; = 8.4 Hz), 12.14 (bs, 1H, NH; exchangeable with D2O); 13C-NMR (DMSO(3). Yellow crystals; yield 2.99 g, 91.5%; m.p. 261C262 C; IR (KBr): 1651 (C=O), 3250 cm?1 (NH); 1H-NMR (DMSO-= 8.4 Hz), 12.12 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H18ClNO2 (327.80): C, 69.62; H, 5.53; N, 4.27 Found: C, 69.82; H, 5.76; N, 3.99. (4). Yellow crystals; yield 3.00 g, 93.0%; m.p. 240C241 C; IR (KBr): 1651 (C=O), 3232 cm?1 (NH); 1H-NMR (DMSO-= 8.4 Hz), 7.48 (d, 1H, -COCH=; = 15.3 Hz), 7.60 (d, 1H, CH=; = 15.3 Hz), 8.01 (d, 2H, ArH; = 8.4 Hz), 12.03 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H21NO3 (323.39): C, 74.28; H, 6.55; N, 4.33 Found: C, 74.40; H, 6.71; N, 4.11. 3.3. General Procedure for the Preparation of Compounds = 17.4, 12.0 Hz), 6.92 (s, 1H, CH-pyrrole), 6.97 (d, 2H, ArH; = 8.6 Hz), 7.25 (bs, 2H, NH2; exchangeable with D2O), 8.01 (d, 2H, ArH; = 8.6 Hz), 12.05 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H21BrN4OS (445.38): C, 53.94; H, 4.75; N, 12.58 Found: C, 53.70; H, 4.60; N, 12.76. = 17.4, 12.0 Hz), 7.58 (s, 1H, CH-pyrrole), 7.47 (bs, 2H, NH2; exchangeable with D2O), 7.77 (d, 2H, ArH; = 7.5 Hz), 7.93 (d, 2H, ArH; = 7.5 Hz), 12.00 (bs, 1H, NH; exchangeable with D2O); 13C-NMR (DMSOand (8). Brown crystals; yield 0.31 g, 81.3%; m.p. 210C211 C; IR (KBr): 1641 (C=O), 3260, 3436 cm?1 (NH); 1H-NMR (DMSO-= 7.7 Hz), 7.93 (d, 2H, ArH; = 7.7 Hz), 11.25 (bs, 1H, NH; exchangeable with D2O), 12.08 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H20BrN3O (386.29): C, 59.08; H, 5.22; N, 10.88 Found: C, 59.26; H, 5.45; N, 10.65. (9). Buff crystals; yield 0.26 g, 78.8%; m.p. 195C196 C; IR (KBr): 1642 (C=O), 3209, 3423 cm?1 (NH); 1H-NMR (DMSO-= 7.7 Hz), 7.78 (d, 2H, ArH; = 7.7 Hz), 11.19 (bs, 1H, NH; exchangeable with D2O), 12.07 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H20ClN3O (341.83): C, 66.76; H, 5.90; N, 12.29 Found: C, 66.53; H, 5.69; N, 12.50. 3.5. General Procedure for the Preparation of Compounds (10). Yellow crystals; yield 0.34 g, 90.1%; m.p. 115C116 C; IR (KBr): Bis-PEG1-C-PEG1-CH2COOH 1646 (C=O), 3423 cm?1 (NH); 1H-NMR (DMSO-(11). Buff crystals; yield 0.26 g, 78.3%; m.p. 160C161 C; IR (KBr): 1643 (C=O), 3433 cm?1 (NH); 1H-NMR (DMSO-= 6.7 Hz), 7.70 (d, 2H, ArH; = 6.7 Hz), 11.97 (bs, 1H, NH; exchangeable with D2O). 13C-NMR (DMSO(12). Buff crystals; yield 0.27 g, 81.0%; m.p. 170C171 C; IR (KBr): 1645 (C=O), 3427 cm?1 (NH); 1H-NMR (DMSO-= 6.9 Hz), 7.62 (d, 2H, ArH; = 6.9 Hz), 11.16 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H22N2O3 (338.40): C, 70.99; H, 6.55; N, 8.28 Found: C, 70.79; H, 6.31; N, 8.47. 3.6. General Procedure for the Preparation of Compounds (13). Brown crystals; yield 0.48 g, 90.2%; mp 180C181 C; IR (KBr): 1219, 1374 (SO2), 1651 (C=O), 3250, 3434 cm?1 (NH, NH2); 1H-NMR (DMSO-(14). Brown crystals; yield 0.43 g, 87.5%; m.p. 150C151 C; IR (KBr): 1219, 1374 (SO2), 1651 (C=O), 3256, 3438 cm?1 (NH, NH2); 1H-NMR (DMSO-= 17.4, 12.0 Hz), 5.53C5.55 (m, 1H, H5-pyrazoline), 6.85 (s, 1H, CH-pyrrole), 7.13 (d, 2H, ArH; = 9.1 Hz), 7.34 (bs, 2H, NH2; exchangeable with D2O), 7.43 (d, 2H, ArH; = 9.1 Hz), 7.53 (d, 2H, ArH; = 8.4 Hz), 7.69 (d, 2H, ArH; = 8.4 Hz), 12.18 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C25H25ClN4O3S (497.01): C, 60.41; H, 5.07; N, 11.27 Found: C, 60.66; H, 5.30; N, 11.03. (15). Buff crystals; yield 0.44 g, 91.1%; m.p. 224C225 C; IR (KBr): 1158, 1307 (SO2), 1650 (C=O), 3263, 3345 cm?1.N’-2-((2-(5,10-Dihydro-[1,2,4]triazino[5,6-b]quinoxalin-3-yl)hydrazono)methyl)-6,6-dimethyl-6,7-dihydro-1H-indol-4(5H)-ylidene)benzohydrazide = 7.6 Hz), 7.38C7.42 (m, 2H, ArH), 12.23 (bs, 3H, 3NH; exchangeable with D2O). (DMSO-= 15.3 Hz), 7.60 (d, 1H, CH=; = 15.3 Hz), 7.76 (d, 2H, ArH; 8.4 Hz), 7.93 (d, 2H, ArH; = 8.4 Hz), 12.14 (bs, 1H, NH; exchangeable with D2O); 13C-NMR (DMSO(3). Yellow crystals; yield 2.99 g, 91.5%; m.p. 261C262 C; IR (KBr): 1651 (C=O), 3250 cm?1 (NH); 1H-NMR (DMSO-= 8.4 Hz), 12.12 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H18ClNO2 (327.80): C, 69.62; H, 5.53; N, 4.27 Found: C, 69.82; H, 5.76; N, 3.99. (4). Yellow crystals; yield 3.00 g, 93.0%; m.p. 240C241 C; IR (KBr): 1651 (C=O), 3232 cm?1 (NH); 1H-NMR (DMSO-= 8.4 Hz), 7.48 (d, 1H, -COCH=; = 15.3 Hz), 7.60 (d, 1H, CH=; = 15.3 Hz), 8.01 (d, 2H, ArH; = 8.4 Hz), 12.03 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H21NO3 (323.39): C, 74.28; H, 6.55; N, 4.33 Found: C, 74.40; H, 6.71; N, 4.11. 3.3. General Procedure for the Preparation of Compounds = 17.4, 12.0 Hz), 6.92 (s, 1H, CH-pyrrole), 6.97 (d, 2H, ArH; = 8.6 Hz), 7.25 (bs, 2H, NH2; exchangeable with D2O), 8.01 (d, 2H, ArH; = 8.6 Hz), 12.05 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H21BrN4OS (445.38): C, 53.94; H, 4.75; N, 12.58 Found: C, 53.70; H, 4.60; N, 12.76. = 17.4, 12.0 Hz), 7.58 (s, 1H, CH-pyrrole), 7.47 (bs, 2H, NH2; exchangeable with D2O), 7.77 (d, 2H, ArH; = 7.5 Hz), 7.93 (d, 2H, ArH; = 7.5 Hz), 12.00 (bs, 1H, NH; exchangeable with D2O); 13C-NMR (DMSOand (8). Brown crystals; yield 0.31 g, 81.3%; m.p. 210C211 C; IR (KBr): 1641 (C=O), 3260, 3436 cm?1 (NH); 1H-NMR (DMSO-= 7.7 Hz), 7.93 (d, 2H, ArH; = 7.7 Hz), 11.25 (bs, 1H, NH; exchangeable with D2O), 12.08 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H20BrN3O (386.29): C, 59.08; H, 5.22; N, 10.88 Found: C, 59.26; H, 5.45; N, 10.65. (9). Buff crystals; yield 0.26 g, 78.8%; m.p. 195C196 C; IR (KBr): 1642 (C=O), 3209, 3423 cm?1 (NH); 1H-NMR (DMSO-= 7.7 Hz), 7.78 (d, 2H, ArH; = 7.7 Hz), 11.19 (bs, 1H, NH; exchangeable with D2O), 12.07 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C19H20ClN3O (341.83): C, 66.76; H, 5.90; N, 12.29 Found: C, 66.53; H, 5.69; N, 12.50. 3.5. General Procedure for the Preparation of Compounds (10). Yellow crystals; yield 0.34 g, 90.1%; m.p. 115C116 C; IR (KBr): 1646 (C=O), 3423 cm?1 (NH); 1H-NMR (DMSO-(11). Buff crystals; yield 0.26 g, 78.3%; m.p. 160C161 C; IR (KBr): 1643 (C=O), 3433 cm?1 (NH); 1H-NMR (DMSO-= 6.7 Hz), 7.70 (d, 2H, ArH; = 6.7 Hz), 11.97 (bs, 1H, NH; exchangeable with D2O). 13C-NMR (DMSO(12). Buff crystals; yield 0.27 g, 81.0%; m.p. 170C171 C; IR (KBr): 1645 (C=O), 3427 cm?1 (NH); 1H-NMR (DMSO-= 6.9 Hz), 7.62 (d, 2H, ArH; = 6.9 Hz), 11.16 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C20H22N2O3 (338.40): C, 70.99; H, 6.55; N, 8.28 Found: C, 70.79; H, 6.31; N, 8.47. 3.6. General Procedure for the Preparation of Compounds (13). Brown crystals; yield 0.48 g, 90.2%; mp 180C181 C; IR (KBr): 1219, 1374 (SO2), 1651 (C=O), 3250, 3434 cm?1 (NH, NH2); 1H-NMR (DMSO-(14). Brown crystals; yield 0.43 g, 87.5%; m.p. 150C151 C; IR (KBr): 1219, 1374 (SO2), 1651 (C=O), 3256, 3438 cm?1 (NH, NH2); 1H-NMR (DMSO-= 17.4, 12.0 Hz), 5.53C5.55 (m, 1H, H5-pyrazoline), 6.85 (s, 1H, CH-pyrrole), 7.13 (d, 2H, ArH; = 9.1 Hz), 7.34 (bs, Rabbit polyclonal to EBAG9 2H, NH2; exchangeable with D2O), 7.43 (d, 2H, ArH; = 9.1 Hz), 7.53 (d, 2H, ArH; = 8.4 Hz), 7.69 (d, 2H, ArH; = 8.4 Hz), 12.18 (bs, 1H, NH; exchangeable with D2O). Anal. Calcd for C25H25ClN4O3S (497.01): C, 60.41; H, 5.07; N, 11.27 Found: C, 60.66; H, 5.30; N, 11.03. (15). Buff crystals; yield 0.44 g, 91.1%; m.p. 224C225 C; IR (KBr): 1158, 1307 (SO2), 1650 (C=O), 3263, 3345 cm?1 (NH, NH2); 1H-NMR (DMSO-= 8.4 Hz), 7.60 (d, 2H, ArH; = 8.4 Hz), 7.70C7.73 (m, 2H, ArH), 11.65 (bs, 1H, NH; exchangeable with D2O). 13C-NMR (DMSO(16). Buff.